|Place of Origin:||China|
|Sertifika:||ISO9001, CQC, GMP and USP etc|
|Minimum Order Quantity:||10gram|
|Packaging Details:||5KG/Cardboard bucket|
|Delivery Time:||5-7 work days|
|Payment Terms:||Bank Transfer, Western Union, Money Gram, Bitcoin, T/T|
|Supply Ability:||600kg/per month|
|Character:||White powder||Boiling point:||472.0±55.0 °C at 760 mmHg|
|flash point:||214.2±24.5 °C||Melting point:||181-183ºC|
99% Anti-estrogen Letrozole(Femara) CAS 112809-51-5 for Cancer Treatment
As for us,the quality of the product comes from production, not quality testing.We can guarantee that most of our products' assay are up to 99%.
As for us, we always keep pace with the market to quote proper and the most competitive price.
As for us, customers are the source of our manufacturing.We always adhere to the customer-oriented development principles. We take sincere concern for customers,and always stand in the customer's position to consider.
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Product Name: Letrozole(Femara)
Synonyms: 4,4'-(1H-1,2,4-TRIAZOL-1-YLMETHYLENE) BIS-BENZONITRILE;FEMARA;CGS-20267;LETROZOL;LETROZOLE;LetrozoleUsp28;Letrozole99%;CGS-20267, Femara
Chemical Properties: white powder
Package: 5KG/Cardboard bucket
Grade: medical grade
Use: Pyrrole type aromatization enzyme inhibitors. Used in the treatment of breast cancer.
storage temp. -20°C Freezer
Density: 1.1±0.1 g/cm3
Melting point: 181-183ºC
Boiling point: 472.0±55.0 °C at 760 mmHg
flash point: 214.2±24.5 °C
Letrozole is a new generation of selective aromatase inhibitors. It is a synthetic benzyl triazole derivative. And it can inhibit aromatase and decrease estrogen levels, therefore eliminate estrogen on tumor growth stimulation. The activity of letrozole in the body is 150-250 times more than that of the first generation of aromatase inhibitors-aminoglutethimide. Because of its high selectivity and no influence on glucocorticoid, mineralocorticoid, and thyroid function, large doses have no inhibitory effect on the secretion of adrenal steroids and therefore have high therapeutic targets.
It's used to the treatment of advanced breast cancer in postmenopausal patients who anti-estrogen ineffective, and early breast cancer.
Take 2.5 mg each time, one time a day. Sex, age, and liver and kidney function are not related to letrozole clinically. Therefore, elderly patients and patients with impaired liver and renal function do not have to adjust the dose.
Distinctions Between Letrozole and Anastrozole:
Letrozole tablets: suitable for advanced breast cancer after menopause, most used in the treatment of anti-estrogen treatment failure after second-line therapy.
Anastrozole: an effective selective inhibitor for three azole aromatase, it inhibits the aromatase relied by cytochrome P-450, further blocks estrogen biosynthesis, which is the main factor to stimulate breast cancer cell growth. The 50% inhibitory concentration (IC50) value of human placenta aromatase is 15 nmol/L.
|CAS No.||112809-51-5||Outer packing||1KG/drum|
|Production date||2017.03.18||shelf life||2019.03.17|
|Items of Analysis||Specification||Results|
|Appearance||White to off-white crystalline powder, odorless||White crystalline powder, odorless|
|Any other individual impurity||≤0.10%||Not detect|
|Total impurities||≤0.5%||Not detect|
|Residue On Ignition||≤0.1%||0.02%|
1.What time do you deliver products we have ordered?
We always deliver products within 24 hours after receiving payments for the most products we sell are in large stock.
2.What kind of shipment ways do you adopt?
We always take expresses to transport products including EMS, DHL, TNT, UPS, FedEx and so on. We will adopt the most suitable express ways according to your products quantities,product category and rate of clearance. As for large order, we also can transport products by sea.
3.Can you provide free sample for us?
Yes, we can do it. The sample is free, but you have to bear the freight.
4.Can we trust your products quality?
We are a kind of company working on chemical industry for thirteens years.Our products meet all standards.And we have our own certificate of analysis. We can provide COA of each batch good.As you know, we can provide sample for you ,so if you are worried about the quality of our product, you can take sample first to have a test, then decide whether purchase in large quantity.
5.Why are your products higher than others?
We always keep pace with the market to quote proper and the most competitive price. What you buy in our company is the guarantee of product quality.Several factors influencing the product price include assay, extraction process, grade,raw materials used and so on. So I suggest that you can take sample to test the quality to determine whether the price is proper.
--------About Our Company--------
Shenzhen Sendi Biotechnology CO., Ltd, owned by Yuancheng group,is a large high-tech chemical enterprise specializing in fine chemicals, flavors, spices, food additives, pharmaceutical raw materials and intermediates.We set research, development, production, operation, sales in one.We have more than 10000 square meters manufacturing shop established in terms of GMP standard from pilot to large production, with advanced equipment.We have perfect quality assurance system and perfect quality control system. And we also have multiple sets of high pressure liquid chromatography, gas chromatography and UV analysis instrument with high efficiency and high sensitivity spectrophotometer, to analyze and control the product.
If you have any question, please feel free to contact me!